TarMiner: automatic extraction of miRNA targets from literature
SSDBM 2015, article No 12
2015
Conference/Workshop
- Contact persons: Ilias Kanellos , Thanasis Vergoulis , Theodore Dalamagas
Abstract.
MicroRNAs (miRNAs) are small RNA molecules that target particular genes and prohibit their expression. Since
many important diseases are related to the expression or
non-expression of particular genes, knowing the miRNAs
that aect these genes can help in nding possible treatments. In the last decade, a large amount of experimental
studies trying to reveal the targets of several miRNAs has
been published. A handful of curated databases that collect
miRNA targets from the literature have been developed to
make this information more easily available. However, due
to the large number of existing published articles, maintaining these databases up-to-date is a tedious task that requires
important resources. In this work we introduce TarMiner,
a pipeline for automatic extraction of miRNA targets that
can facilitate the curation process of databases that maintain miRNA validated targets.